Mobilization of Plasmids and Chromosomal DNA Mediated by the SXT Element, a Constin Found in Vibrio cholerae O139
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چکیده
منابع مشابه
Mobilization of plasmids and chromosomal DNA mediated by the SXT element, a constin found in Vibrio cholerae O139.
The Vibrio cholerae SXT element encodes resistance to multiple antibiotics and is a conjugative, self-transmissible, and chromosomally integrating element (a constin). Excision and self-transfer of the SXT element require an element-encoded integrase. We now report that the SXT element can also mobilize the plasmids RSF1010 and CloDF13 in trans as well as chromosomal DNA in an Hfr-like manner. ...
متن کاملVibrio cholerae SXT Element, Laos
To the Editor: The SXT element is a Vibrio cholerae–derived ICE (integrating and conjugative element), which has also been referred to as a conjugative transposon (1) or a constin (2). ICEs excise from the chromosomes of their hosts, transfer to a new host through conjugation, and then integrate into the chromosome again. SXT element was originally isolated in 1993 from a V. cholerae O139 clini...
متن کاملSXT constin among Vibrio cholerae isolates from a tertiary care hospital
BACKGROUND & OBJECTIVES The SXT element, also known as 'constin' (conjugable, self transmissible, integrating element) is an integrating conjugative element (ICE) in Vibrio cholerae discovered in the chromosome of epidemic V. cholerae O139 strain MO10 (SXT MO10 ) which arose in late 1992 in Chennai, India. SXT related ICEs have become widespread and currently, most if not all Asian V. cholerae ...
متن کاملMolecular analysis of antibiotic resistance gene clusters in vibrio cholerae O139 and O1 SXT constins.
Many recent Asian clinical Vibrio cholerae E1 Tor O1 and O139 isolates are resistant to the antibiotics sulfamethoxazole (Su), trimethoprim (Tm), chloramphenicol (Cm), and streptomycin (Sm). The corresponding resistance genes are located on large conjugative elements (SXT constins) that are integrated into prfC on the V. cholerae chromosome. We determined the DNA sequences of the antibiotic res...
متن کاملEmergence and evolution of Vibrio cholerae O139.
The emergence of Vibrio cholerae O139 Bengal during 1992-1993 was associated with large epidemics of cholera in India and Bangladesh and, initially, with a total displacement of the existing V. cholerae O1 strains. However, the O1 strains reemerged in 1994 and initiated a series of disappearance and reemergence of either of the two serogroups that was associated with temporal genetic and phenot...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2000
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.182.7.2043-2047.2000